Natural Genetic Variation in Lycopene Epsilon Cyclase Tapped for Maize Biofortification

Natural genetic variation in lycopene epsilon cyclase tapped for maize biofortification.

Dietary vitamin A deficiency causes eye disease in 40 million children each year and places 140 to 250 million at risk for health disorders. Many children in sub-Saharan Africa subsist on maize-based diets. Maize displays considerable natural variation for carotenoid composition, including vitamin A precursors alpha-carotene, beta-carotene, and beta-cryptoxanthin. Through association analysis, ...

Genetic and Physiological Analysis of Iron Biofortification in Maize Kernels

BACKGROUND Maize is a major cereal crop widely consumed in developing countries, which have a high prevalence of iron (Fe) deficiency anemia. The major cause of Fe deficiency in these countries is inadequate intake of bioavailable Fe, where poverty is a major factor. Therefore, biofortification of maize by increasing Fe concentration and or bioavailability has great potential to alleviate this ...

Genetic modification of tomato with lycopene β–cyclase gene produces high β–carotene and lycopene fruit

Transgenic Solanum lycopersicum plants expressing an additional copy of lycopene β– cyclase (LCYB) from Nicotiana tabacum, under the control of the Arabidopsis polyubiquitin promoter (UBQ3), have been generated. Expression of LCYB was increased some 10-fold in ripening fruit compared to vegetative tissues. The ripe fruit showed an orange pigmentation, due to increased levels (up to 5-fold) of β...

Genetic variation in natural populations

Natural genetic variation for improving crop quality.

The narrow genetic basis of many crops combined with restrictions on the commercial use of genetically modified plants, has led to a surge of interest in exploring natural biodiversity as a source of novel alleles to improve the productivity, adaptation, quality and nutritional value of crops. Genetic methodologies have been applied to natural variation to improve quality aspects that are assoc...